Description
To obtain a challenging position in pharmaceutical industry involved in drug discovery and quality control that takes advantage of my experience in medicinal chemistry, organic synthesis and analytical laboratory skills. Willing to make an impact for the success and growth of a cutting edge company by utilizing my skills and experience. Professional Summary: * Experienced in medicinal chemistry, organic synthesis and quality control. * Designed, synthesized, and purified small molecule ligands for various targets including CNS, ion channel and G protein-coupled receptors (GPCR) * Successful application of structure-activity studies to optimize lead compounds * Experience in both modern and classical laboratory techniques such as ISCO purifications, UPLC, HPLC, UV-Vis, microwave synthesis, H-Cube, lyophilization, NMR using top-spin software, chromatography technique, TLC, IR., protein purification, UF/ DF, Chromatography * Experienced in laboratory software and database such as electronic laboratory note book, data visualization software (D360), ACD-Spectrus, and Chemdraw, Empower, Chemstation, MassLynx, SPSS statistical data base, and SAS clinical data base. * Experienced in executing literature searches in a number of bibliographic databases (eg, Sci-Finder, Reaxys, PubMed, OVID, etc) and experience in conducting systematic literature reviews (produce tabular and / or narrative summaries of the relevant articles) * Knowledge & experience on troubleshooting of analytical instruments, such as HPLC (High Performance Liquid Chromatography) GC/MS, LC/MS. * Performed under CGMP/GLP work environment and follow SOP * Effectively participated with third party marketing and product supplier to ensure on time delivery and perform the necessary maintenance of the lab instruments & equipment. * Knowledge of current FDA guidelines and regulations, IND/NDA/ANDA, 510 (k), PMA submissions, post approval compliance. Familiarity with the purpose of GMPs, GLPs, GCPs and other GXPs in Clinical Investigations, * Proven team player and skillful communicator both in oral and written. * Communicate clearly and effectively to diverse audiences through both written reports and oral presentations. * Fully participated in brain storm meeting and generated new ideas and implemented the necessary reaction methodology for the R&D group. * Display and actively promote teamwork in completing work assignments.
