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William H

Innovative translational research program director - able to bridge basic and clinical research

Occupation:

Physician

Location:

Coralville, IA

Education Level:

Medical Degree

Will Relocate:

YES

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I am looking to explore opportunities as a senior research director in the pharmaceutical or biotech industry. I have extensive experience in basic and clinical research in atherosclerosis, hypertension, lipids, diabetes and obesity (>100 papers, multiple NIH grants). I am program director of a Clinical Research Center, and Director of a Division of Clinical Pharmacology. My training included work in a intensive phase I-III clinical trials unit doing first-in-human studies, including anti-anginals, anti-hypertensive, anti-stroke and anti-arrhythmic drugs. I have participated in multiple phase IIi and IV trials in hypertension, obesity, hyperlipidemia, diabetes, Raynaud's syndrome and atherosclerosis.

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COMPANY POSITION HELD DATES WORKED

University of Iowa (Confidential) 1/1995 - 1/2009
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SCHOOL MAJOR YEAR DEGREE

University of Sheffield Medical 1995 Medical Degree
University of Sheffield Research doctorate 1995 Doctorate Degree
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Highlights:

1. First report of vascular effects of and non-selective endothelin receptor agonists and antagonists in humans (Lancet 1994 [>300 citations] and Circulation 1995 & 1996). 2. Seminal paper on the effects of leptin on sympathetic nerve activity (JCI 1997; >500 citations). Followed by over 20 papers on cardiovascular and metabolic regulation in obesity, including recent papers in Diabetes (2008) and JCI (2004). 3. Austin Doyle Young Investigator Award - International Society of Hypertension 1998. 4. Demonstration that inhibition of xanthine oxidase activity reverses vascular damage caused by smoking in humans (Circulation 2003, ATVB 2007). 5. Elected member, American Society of Clinical Investigation 6. Recent development of multidisciplinary research teams exploring links between subclinical vascular phenotypes and kidney disease (both renal transplant and ESRD), and also psychiatric disease (both cognitive decline and atypical antipsychotic use).

Companies I like:

Merck, Pfizer, Abbott, Roche, GSK, Astra-Zeneca, BMS, Genetech, innovative biotech companies.

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Major advances in understanding of mechanisms of obesity and atherosclerosis
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