University Of Pennsylvania School Of Medicine, Department Of Surgery Of Urology, Work Values

Daily Duties at University Of Pennsylvania School Of Medicine, Department Of Surgery Of Urology, :

Built the Malkowicz Research Laboratory from the ground up, leading the preparation of all grant proposals, scientific manuscripts, IACUC, IRB, and Safety documents; assumed responsibility for over 90% of all experimental research while engaging in the design and coordination of all research strategy and molecular tools for all studies. Pioneered the recreation of a laboratory and associated tool set to lead the research into a gene of unknown function; developed Adeno- and Lenti-virus for transduction of TERE1 and TBL2 cDNAs and MiRNAs to modulate gene expression, and characterize cellular phenotypes in bladder and prostate cancer cell lines. Evaluate the role of loss of expression of the TERE1 protein in progression of urological cancers and characterize interacting proteins: TBL2, and APOE. Provided academic leadership and mentoring to technicians, laboratory assistants, graduate students, and post-doctoral fellows.

What they like about University Of Pennsylvania School Of Medicine, Department Of Surgery Of Urology, :

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Tags

cell and molecular, cancer research, cell signaling, gene regulation, epigenetics, metabolism, Microscopy, Virology, nuclear receptors, steroid and lipid metabolism, prostate cancer, renal cancer, breast cancer, genomics, mitochondria, cloning and mutagenesis, multidrug resistance, chromosomal translocations, inducible expression vectors, chromatin immunoprecipitation ChIP-Seq, CRISPR/CAS gene editing, bioinformatics software

Skills

Mechanisms of Cancer Progression, Gene Expression, Regulation, and Epigenetics, Cell signaling pathways and Metabolism, Analysis of protein complexes and interactions, Genomics: promoters, translocations, CRISPR gene edits, Engineering cancer cell lines: prostate, kidney, bladder, breast, ovarian, colorectal, pancreatic, sarcoma, Using Animal Models, Record of Scientific Publication, Supervising Laboratory Personnel, Experimental design, trouble shooting, data analysis, Successful record of collaborations, Authoring Research Grants, Experienced in Industrial and Academic Settings, Managing Laboratory Documentation, Launching Laboratory Operations

These are some of the questions we asked our climbers about their experiences with University Of Pennsylvania School Of Medicine, Department Of Surgery Of Urology, :