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Washington University, St. Louis, Mo Work Values
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Daily Duties at Washington University, St. Louis, Mo:
I worked in the Lab of Dr. Lee Ratner where I discovered that HIV envelope signaling through the G protein coupled HIV coreceptors, CCR5 and CXCR4, results in Gαq induced Rac-1 activation and actin remodeling required for virus-cell fusion and virus entry. The signaling cascade activated downstream of Gαq was also elucidated and these results were published in the Journal of Virology in September, 2008. During my graduate work, I also determined the signaling pathway activated by Rac-1 that mediates the actin rearrangements necessary for pore formation and enlargement and these results were published in Plos Pathogens in June, 2010. In addition, my research showed that clinically tested inhibitors including imatinib, dasatinib and nilotinib currently used for treatment of chronic myeloid leukemia, significantly reduced HIV infection of multiple cell types including primary cells, providing a new focus on cellular factors as drug targets for HIV.
What they like about Washington University, St. Louis, Mo:
Organizations with strong, centralized leadership are particularly attractive to you. You require a work environment with leadership that aggressively seeks to expand and grow the business and does so in a visible and decisive manner. In general you prefer to work in an environment in which there is a strong link between leadership, its actions, and a strong set of company-wide values.
Tags
Microbiology, Immunology, Cell biology, FACS, ELISA, high throughput screens, cell based assays, Python, quantitative RT-PCR, cloning, biochemical signaling networks
Skills
tissue culture of cell lines and primary cells, development, optimization and implementation of cell-based assays, biochemical assays, quantitative RT-PCR, automated liquid handling systems, flow cytometry, immunoassays, Western blots, ELISA, cloning, protein expression and purification, fluorescence microscopy, transfection and retroviral transduction of mammalian cells, RNA interference, BioTek and Thermo Scientific cell dispensers, BioTek plate washers, microtiter plate readers, Python programming, pathway analysis software, FACS analysis software, statistical analysis, Microsoft office
Information about Washington University, St. Louis, Mo
Company Rank: Not Available
Average length of employment : 6 years
Average salary of employees: $85,000
These are some of the questions we asked our climbers about their experiences with Washington University, St. Louis, Mo:
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| Were your performance expectations clearly communicated? | 0.0 |
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| Did you feel like your personal contribution was important? | 0.0 |
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| Was your career path clearly outlined and discussed? | 0.0 |
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| I would recommend this as a place of employment. | 0.0 | |
| I believe in the purpose of this organization. | 0.0 | |
| I would work for this organization again. | 0.0 | |
| I feel employees are fairly compensated. | 0.0 |
