Seattle Genetics, Inc. Work Values

Daily Duties at Seattle Genetics, Inc.:

As a member of the Cell Culture group my primary responsibilities are feed and media optimization and bench-scale bioreactor process development. - Perform fed-batch studies for optimization of feed and media. - Responsible for operation of bioreactors at multiple scales for purpose of optimizing cell culture conditions as well as generating material for other groups. - Expansion of cell cultures from frozen vials to larger scale using shake flasks and wave bags to support bioreactor operations. - Evaluated potential alternative instrumentation for measuring metabolites in cell culture. - Additional duties include monitoring the incubators, ViCell units, and Cedex. - Analyze results of experiments in electronic notebooks. Write detailed technical reports and present findings at meetings. - Served on Health and Safety Committee in 2007. - Provided technical support for process validation (PV) campaign. Led or second contributor for numerous bioreactor and shake flask studies supporting PV or qualification of raw materials for the commercial campaign. - Served as Project Manager for two GMP cell banks at contract manufacturing organization (CMO). - Led a multi-cell line bioreactor run. Worked with cell line development group closely during this run. - Performed a media screening study to support commercial manufacturing which showed that a specific lot of raw material was causing filtration issues. - Performed follow-up studies under pressure which confirmed the finding. The observation of the filtration issue prevented impacting timelines and drug supply. - Populated the technical report database for inspection activities. - Troubleshoot issues at CMOs by performing scale-down experiments. - Acted as a point person for legal during freedom to operate inquires. - Required collaboration with outside vendors to obtain information. - Produced cell banks that will supply cells for process development studies. - Helped with the process monitoring database. Defined data fields for entry and also helped with spot verification to ensure accuracy.

What they like about Seattle Genetics, Inc.:

The social vibrance of a hiring firm is very important to you. Your ability to make and maintain friendships there is a critical part of your decision. You would likely be dissatisfied with a workplace that is quiet, cold, or otherwise not particularly social. When you investigate a new hiring company, ask recruiters, managers, and potential co-workers about the social life and opportunities there. This is especially important when you are relocating; moving dramatically alters your social sphere both inside and outside the workplace.

Tags

Entry Level, Chemical Engineer, Process Engineer, Software Engineer, Project Engineer, Environmental Engineer, Energy Engineer

Skills

Microsoft Word, Microsoft Excel, Microsoft Outlook, Microsoft Powerpoint, UV-Vis Spectrometer, Bioreactors (3, 7, 15, 35 L), Wave Bioreactor, ViCell Cell Counter, Cedex Cell Counter, YSI, BioProfile 100, pHOx, ABL805, LAL Endotoxin Testing, ELISA (HCP, Protein A), UF/DF Purification, HPLC (SEC, HIC, Reversed Phase, Protein G)

These are some of the questions we asked our climbers about their experiences with Seattle Genetics, Inc.: