Elan Pharmaceuticals Work Values

Daily Duties at Elan Pharmaceuticals:

Animal Science Core Group Expertise with in vivo procedures using advanced technology and tools to innovate and enable in vivo support • Scheduled and participated in in vivo experiments across departments • Tested compounds in support of PK ADME, Pharmacology and Research Toxicology efforts • Promoted innovative in vivo techniques /skills • Trained and managed verification of animal use handling proficiencies and certifications • Harmonized study protocols, data/sample recording across Animal Core, Pharmacology, DMPK, and Biology to keep tailored to each different experiment Behavior / Functional Assessment for AD and PD models Set-up and implemented the following behavioral assays in support of target validation, compound screening and selection: • Mouse cognition paradigms: Spontaneous Alternation, Contextual Fear Conditioning, Novel Object Recognition • Mouse and rat sensorimotor paradigms: Locomotor Activity, Challenge Beam, Pole Test, Rotarod, Cylinder Task, Rotometer Provided in vivo biology support in animal models to enable efforts in Autoimmune program • Induction and treatment of Experimental Autoimmune Encephalitis (EAE) in rat and guinea pig • Histological analysis: scoring methods of spinal cords for EAE model (H&E, Weil, and Iba-1, CD4, CD8, etc.) • Pharmacokinetic/pharmacodynamic experiments in rats, guinea pigs, and mice • Assisted in radioactive studies to support CNS homing efforts • Served on IACUC reviewing animal care and use protocols Conducted research in Analgesia program to validate novel neuropathic and inflammatory pain targets • Spared Nerve Injury and Chung model surgeries • Inflammatory Pain Models (Complete Freund’s Adjuvant and Carrageenan) • Mechanical von Frey Testing and Thermal Hyperalgesia (Hargreaves Method)

What they like about Elan Pharmaceuticals:

A hiring company that offers alternative approaches to pay, performance bonuses, and/or equity in the firm is very attractive to you. You're generally less interested in working for an organization offering only traditional, salary-based compensation, one with limited opportunity to acquire equity in the firm, or one that does not actively promote skill development. In addition, you are more likely to choose a company that offers a variety of internal career options, with defined career paths. You view the learning of new skills and development of your expertise as key to your career advancement. These aspects of an organization may become even more important to you as you progress in your field, and are especially critical if you change career or occupation.

Tags

in vivo, pre-clinical, dosing, surgical, rodent, behavioral, behavior testing, in vivo assay, Graphpad Prism, Excel, Microsoft Word, i.v., s.c., p.o., i.m., i.p., intrathecal, routes of administration, animal, veterinary, vivarium

Skills

These are some of the questions we asked our climbers about their experiences with Elan Pharmaceuticals: