Elan Pharmaceuticals Work Values

Daily Duties at Elan Pharmaceuticals:

Animal Science Core Group Expertise with in vivo procedures using advanced technology and tools to innovate and enable in vivo support • Scheduled and participated in in vivo experiments across departments • Tested compounds in support of PK ADME, Pharmacology and Research Toxicology efforts • Promoted innovative in vivo techniques /skills • Trained and managed verification of animal use handling proficiencies and certifications • Harmonized study protocols, data/sample recording across Animal Core, Pharmacology, DMPK, and Biology to keep tailored to each different experiment Behavior / Functional Assessment for AD and PD models Set-up and implemented the following behavioral assays in support of target validation, compound screening and selection: • Mouse cognition paradigms: Spontaneous Alternation, Contextual Fear Conditioning, Novel Object Recognition • Mouse and rat sensorimotor paradigms: Locomotor Activity, Challenge Beam, Pole Test, Rotarod, Cylinder Task, Rotometer Provided in vivo biology support in animal models to enable efforts in Autoimmune program • Induction and treatment of Experimental Autoimmune Encephalitis (EAE) in rat and guinea pig • Histological analysis: scoring methods of spinal cords for EAE model (H&E, Weil, and Iba-1, CD4, CD8, etc.) • Pharmacokinetic/pharmacodynamic experiments in rats, guinea pigs, and mice • Assisted in radioactive studies to support CNS homing efforts • Served on IACUC reviewing animal care and use protocols Conducted research in Analgesia program to validate novel neuropathic and inflammatory pain targets • Spared Nerve Injury and Chung model surgeries • Inflammatory Pain Models (Complete Freund’s Adjuvant and Carrageenan) • Mechanical von Frey Testing and Thermal Hyperalgesia (Hargreaves Method)

What they like about Elan Pharmaceuticals:

Working for a company with an emphasis on social values and helping society is a clear and important priority for you - a critical factor in who you choose to work for. In contrast to other factors, you place an organization's reputation for fairness and concern for the community above most other aspects of the company. As you search for a new job opportunity, it is usually possible to find out if the company is involved in the community and/or if it is addressing problems and issues in society. Pay special attention to non-profit organizations and those specifically involved in social action. Moreover, speaking with current and former employees should enlighten you to perceptions of the fairness of the company's leaders and the treatment of employees.

Tags

in vivo, pre-clinical, dosing, surgical, rodent, behavioral, behavior testing, in vivo assay, Graphpad Prism, Excel, Microsoft Word, i.v., s.c., p.o., i.m., i.p., intrathecal, routes of administration, animal, veterinary, vivarium

Skills

These are some of the questions we asked our climbers about their experiences with Elan Pharmaceuticals: