Dept. Of Cancer Biology And Pharmacology, University Of Illinois College Of Medicine At Peoria, Peoria, Il. Work Values

Daily Duties at Dept. Of Cancer Biology And Pharmacology, University Of Illinois College Of Medicine At Peoria, Peoria, Il. :

•Studies on Protein-protein interaction and its biological implication on malignant transformation: Demonstrated that tumor invasion and SPARC overexpression are closely associated and involve PI3-K and RhoA GTPase shedding light on potential targets for inhibiting tumor cell infiltration in gliomas, and possibly, other cancers. •Implementation of RNAi technology: Showed combined use of inhibitors of MMP9 and inhibitors of plasmin/Plg activation system has a synergistic effect in inhibiting breast cancer growth and progression and has significant clinical implications. •Established various methods for efficient use of chemicals and other resources at the laboratory. •Completed the tasks assigned within deadlines and delivered excellent and consistent results.

What they like about Dept. Of Cancer Biology And Pharmacology, University Of Illinois College Of Medicine At Peoria, Peoria, Il. :

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Tags

Research, Molecular Biology, Biochemistry, Cell Biologist, Drug Discovery, Cell Culture

Skills

Drug Discovery: FPLC, HPLC, protein purification techniques- gel filtrations and affinity chromatography, SDS-PAGE, Western blotting, RIA, ELISA, fluorescence microscopy, Immunohisto/cytochemistry, Fibrin and Gelatin zymography, EMSA, Microinjection and , Molecular biology:Transformation, restriction analysis, RT-PCR, cloning and Gene knock out experiments, Nuclease protection assay, RNAi techniques, adenoviral and retroviral mode of transfection, Single cell proliferation assay, Southern and Northern blot, Cell culture:Isolation of vascular smooth muscle cells from the aorta of mice, rat and rabbit, Isolation of monocytes and neutrophils from peripheral blood from human and mice, isolation of endothelial cells from human umbilical cord, Coculture system, Ra, Others: FACS analysis, Chromatin Immunoprecipitation (chIP) assay, qRT-PCR and other gene expression assays, CAT assay,Raising orthotopic breast tumors, pancreatic tumors and lung tumors in nude and SCID mice.

These are some of the questions we asked our climbers about their experiences with Dept. Of Cancer Biology And Pharmacology, University Of Illinois College Of Medicine At Peoria, Peoria, Il. :