Fb Reagents/ Harvard Medical School Work Values

Daily Duties at Fb Reagents/ Harvard Medical School:

• Synthesized potent inhibitor of protein-protein interactions in cancer and immunology. • Fragment based small molecule synthesis using Medicinal and Organic Chemistry. • Identify hits from above screening by applying Medicinal Chemistry techniques. • Study protein-protein interactions and High-throughput screening of small molecules and fragment library using florescence polarization and NMR assay. • Grow bacteria; make lysates, reagents, and buffers to purify proteins, peptides. • Synthesis, purification and analysis of peptides, proteins and small molecules by HPLC, LC-MS, SEC, KF, MS-MS, NMR, UV-Vis, IR, SDS-PAGE, DSC, TGA, Prep-TLC. • Lead optimization by designing multi-step synthetic routes for the production of library of drug-like compounds using click chemistry and structure-based synthesis. • Worked closely in team of protein structural biologist, biochemist, computational chemist and X-ray crystallographers.

What they like about Fb Reagents/ Harvard Medical School:

You give high priority to hiring firms with prestige. Market reputation and prestige of a firm may be determined through on-line research, and conversations with individuals working in your target industry. Note that firms "in the public eye" receive a great deal more critical publicity and attention than those operating with more anonymity. So as you assess your employment opportunities, be sure to seek out the positive aspects of the firm's reputation in addition to noting negative publicity the company may have received.

Tags

Organic Chemistry, Medicinal Chemistry, Analytical Chemistry, HPLC, LC-MS, NMR, FPLC, SDS-PAGE, UV-Vis, Prep-TLC, TGA, DSC, Research Scientist

Skills

• HPLC, LC-MS, SEC, KF, MS-MS, NMR, UV-Vis, IR, SDS-PAGE, DSC, TGA, Prep-TLC, GC and fluorescence., • Organic and Medicinal Chemistry: Expert in designing synthetic routes, fragment, structure, NMR, based synthesis, parallel and combinatorial synthesis, click chemistry, sugar, protein, lipid chemistry, bioconjugates. , • Analytical Chemistry: purification and structural elucidation of chemically and biologically derived drug substances by chromatography

These are some of the questions we asked our climbers about their experiences with Fb Reagents/ Harvard Medical School: