Fordham University (Research Experiences) Work Values

Daily Duties at Fordham University (Research Experiences):

read relavant research paper from journals such as "cell" "nature" and "science". aim project and design the method to use and the time schedule. The Research Associate will: • Under the direction of a senior scientist, perform a variety of molecular and cell based assays to support application development of a novel rare cell analysis platform • Follow established protocols for running instruments and associated assays • Aid in the development of new methods by running experiments and keeping well documented records • Operate Fluxion's rare cell analysis system for the processing of clinical and research samples • Maintain cell cultures and prepare cell suspensions and reagents for experimental use • Communicate experimental results to members of the technical staff and provide recommendations for further improvements to experimental methods • Maintain a thorough and detailed laboratory notebook to document experimental results The candidate must have theability to apply scientific and engineering principles to solve complexproblems and have a proven record of innovation. A good understanding of cell physiology,metabolism, and cell biology is required, as well as an understanding ofprotein production and process development in mammalian systems. Previous experience with laboratorymanagement or in a GMP manufacturing environment is a plus. The candidate must be highly self-motivated,have excellent organization and communication skills, and be willing to workindependently or as part of a large multi-disciplinary team. Molecular/Cellular Biologists Candidates will have experience with cloning and expression of cell surface and soluble proteins. Experience with design and construction of fusion proteins is required. Mammalian transfection experience required. Candidates will have skills necessary to assess transfection/expression efficiency (FACS for tag, Western blot, ELISA, etc.). In vitro cell growth and antibody centric cell based assays such as ADCC, proliferation and FACS experience is useful. Candidates from Research Associate to Scientist level sought. The candidate will be responsible for developmentand implementation of robust, high titer recombinant production processes usingmammalian systems (primarily CHO cells) within the Late Stage Cell CultureProcess Development Department. The candidate will alsobe required to investigate and implementtechnologies/strategies to optimize recombinant protein production. studies,authoring and reviewing technical reports and documentation to supportregulatory filings, and to represent the department on various projectteams. The candidate will be required toroutinely present project proposals and data at project, department and companymeetings. There is potential opportunityfor supervisory responsibility. Who you are The candidate must have theability to apply scientific and engineering principles to solve complexproblems and have a proven record of innovation. A good understanding of cell physiology,metabolism, and cell biology is required, as well as an understanding ofprotein production and process development in mammalian systems. The candidate must be highly self-motivated,have excellent organization and communication skills, and be willing to workindependently or as part of a large multi-disciplinary team. target gene location, DNA purification, PCR, real time PCR, SDS gel, ELISA, NCBI, Western blot, DNA sequencing, cell culture, protein extract, cell membrane protein extract, biotin-avidin systems, ChIP, perl/java

What they like about Fordham University (Research Experiences):

Organizations with strong, centralized leadership are particularly attractive to you. You require a work environment with leadership that aggressively seeks to expand and grow the business and does so in a visible and decisive manner. In general you prefer to work in an environment in which there is a strong link between leadership, its actions, and a strong set of company-wide values.

Tags

research, molecular biology, science, biochemistry, immunology, zoology, PERL, bioinformatics, ncbi, hospital

Skills

Molecular Biology/Genomics: DNA/RNA preparation, Gene expression analysis (Northern blot, Real time quantitative PCR), primer design including Taqman probes, Recombinant DNA techniques (DNA sequencing, cDNA cloning, plasmid/vector construction of tagg, Biochemistry/Cell Biology/Histology: PAGE, Western Blot, ELISA, Histology, Cell culture/Primary culture, Transformation/Transfection, Selection of Stable cell lines. Immunostaining., Physiology/Electrophysiology: Animal Handling (rodents etc), Patch-Clamping., Bioinformatics/Statistics/Computer Sciences: NCBI, Blast, Swiss-Prot, Windows/Mac/Unix, Perl/Java, Excel, Prism, SYSTAT.

These are some of the questions we asked our climbers about their experiences with Fordham University (Research Experiences):