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Drug Safety Specialist

To obtain a position in a clinical research setting with emphasis in drug safety and phamacovigilance where my medical and research background can be highly valuable.

Clinical Research

Medford, MA

About Me

Industry:	Science & Biotech
Occupation:	Clinical Research
Highlights:	PUBLICATIONS 1. Breault DT, Min IM, Carlone DL, Farilla LG, Ambruzs DM, Henderson DE, Algra S, Montgomery RK, Wagers AJ, Hole N. Generation of mTert-GFP mice as a model to identify and study tissue progenitor cells. PNAS, 105(30):10420-10425, 2008. 2. Noushmehr H, D'Amico E, Farilla L, Hui H, Wawrowsky KA, Mlynarski W, Doria A, Abumrad NA, Perfetti R. Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion. Diabetes, 54(2):472-81, 2005. 3. Urusova IA, Farilla L, Hui H, D'Amico E, Perfetti R. GLP-1 inhibition of pancreatic islet cell apoptosis. Trends Endocrinol Metab., 15(1):27-33, 2004. 4. Bulotta A, Farilla L, Hui H, Perfetti R. The role of GLP-1 in the regulation of islet cell mass. Cell Biochem Biophys., 40(3 Suppl):65-78, 2004. 5. Farilla L, Bulotta A, Hirshberg B, Li Calzi S, Khoury N, Noushmehr H, Bertolotto C, Di Mario U, Harlan DM, Perfetti R. Glucagon-like peptide-1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets. Endocrinology, 144(12):5149-58, 2003. 6. Farilla L, Hui H, Bertolotto C, Kang E, Bulotta A, Di Mario U, Perfetti R. Glucagon-like peptide-1 promotes islets cell growth and inhibits apoptosis in Zucker Diabetic Rats. Endocrinology, 143(11):4397-4408, 2002. 7. Hui H, Farilla L, Merkel P, Perfetti R. The short half-life of Glucagon-like peptide-1 in plasma does not reflect its long-lasting beneficial effects. European Journal of Endocrinology, 146(6):863-9, 2002. 8. Farilla L, Tiberti C, Luzzago A, Yu L, Eisenbarth GS, Cortese R, Dotta F, Di Mario U. Application of phage display peptide library to autoimmune diabetes: identification of IA-2/ICA512 BDC dominant autoantigen epitopes. European Journal of Immunology, 32(5):1420-7, 2002. 9. Pichurin P, Yan XM, Farilla L, Guo J, Chazenbalk GD, Rapoport B, McLachlan SM. Naked TSH receptor DNA vaccination: A TH1 T cell response in which interferon-gamma production, rather than antibody, dominates the immune response in mice. Endocrinology, 142(8):3530-3536, 2001. 10. Xiong Z, Farilla L, Guo J, McLachlan S, Rapoport B. Does the autoantibodies immunodominant region on thyroid peroxidase include amino acid residues 742-771? Thyroid, 11(3):227-23, 2001. 11. Farilla L, Dotta F, Di Mario U, Rapoport B, McLachlan SM. Presence of interleukin 4 or interleukin 10, but not both cytokines, in pancreatic tissue of two patients with recently diagnosed diabetes mellitus type 1. Autoimmunity, 32(3):161-166, 2000. 12. Cilio CM, Bosco S, Moretti C, Farilla L, Savignoni F, Colarizi P, Multari G, Di Mario U, Bucci G, Dotta F. Congenital autoimmune diabetes Mellitus. New Engl. J. Med, 342(20):1529-1531, 2000. 13. Mennuni C, Santini C, Lazzaro D, Dotta F, Farilla L, Fierabracci A, Bottazzo GF, Di Mario U, Cortese R, Luzzago A. Identification of a novel type 1 diabetic-specific epitope by screening phage libraries with sera from pre-diabetic patients. J. Mol. Biol., 268(3): 599-606, 1997. 14. Misasi R, Dionisi S, Farilla L, Carabba B, Lenti L, Di Mario U, Dotta F. Gangliosides in autoimmune diabetes. Diab. Met. Rev., 13(3):163-179, 1997. 15. Dotta F, Dionisi S, Farilla L, Di Mario U. The use of immunological markers in IDDM after more than 20 yeras from ICA description. Diabetes Metab. Rev. 12(2):121-6, 1996 16. Mennuni C, Santini C, Dotta F, Farilla L, Di Mario U, Fierabracci A, Bottazzo G, Cortese R, Luzzago A. Selection of phage-displayed peptides mimicking type 1 diabetes-specific epitopes. J. Autoimmunity, 9(3):431-436, 1996. 17. Dotta F, Dionisi S, Misasi R, Tiberti C, Anastasi E, Carabba B, Farilla L, Di Mario U. Ganglioside antigens in autoimmune diabetes. Diab. Nutr. Metab., 9:215-220, 1996. 18. Dotta F, Dionisi S, Farilla L, Di Mario U. Prediction of Type 1 diabetes 20 years after the discovery of cytoplasmic ICA. Diab. Met. Rev. 12:121-126, 1996. 19. Dionisi S, Sentimentale A, Farilla L, Carabba B, Di Mario U, Dotta F. Gli autoanticorpi diretti contro il ganglioside pancreatico GM2-1 nel topo NOD appartengono alla sottoclasse IgG1. [Autoantibodies Against GM2-1 Ganglioside in NOD Mice Belong to the IgG-1 Subclass]. Atti del X Congresso Nazionale A.M.D.: 355-359, 1995. 20. Farilla L, Dionisi S, Carabba B, Previti M, Sentimentale A, Lenti L, Di Mario U, Dotta F. Ganglioside insulare GM2-1: identificazione di una nuova struttura glicolipidica coinvolta nell�autoimmunit� beta cellulare. [Islet Ganglioside GM2-1 Identification of a New Glycolipid Molecule Involved in Beta-Cellular Autoimmunity]. Atti del X Congresso Nazionale A.M.D.: 351-354, 1995. 21. Sentimentale A, Tiberti C, Dionisi S, Farilla L, Torresi P, Andreani D, Di Mario U, Falorni A, Lernmark A, Dotta F. Il diabete di tipo 1 quale malattia autoimmuneneuroendocrina. [Type-1 Diabetes as a Neuroendocrine Autoimmune Disease]. Atti del X Congresso Nazionale A.M.D.: 345-349, 1995.
Ideal Companies:	Novartis, Merck, Pfizer, Biogen, Millenium pharmaceuticals, Vertex, Parexel, Wyeth, FDA

Education level:	Medical Degree
Will Relocate:	No
Location:	Medford, MA